What the research reports
View evidenceYeast and mouse Sir2 studies characterised NAD dependence in their stated enzyme systems.
Imai et al., Nature, 2000 · PubMed · Smith et al., PNAS, 2001 · PubMed
Image 01 / 01Research compound
NAD+
Redox coenzyme — sirtuin and PARP substrate
Research compoundCA$50.00
NAD+/
CA$50.00
How it works
A PARP biochemical study characterised NAD cleavage and consumption in its stated system.
Kleine et al., Journal of Biological Chemistry, 2008 · PubMed
Where the evidence comes from
View evidenceNAD+ findings shown here come from yeast and mouse Sir2 systems and PARP biochemical systems.
Imai et al., Nature, 2000 · PubMed · Smith et al., PNAS, 2001 · PubMed · Kleine et al., Journal of Biological Chemistry, 2008 · PubMed
What's still open
NAD+ findings shown here remain limited to the cited enzyme systems.
Imai et al., Nature, 2000 · PubMed · Smith et al., PNAS, 2001 · PubMed · Kleine et al., Journal of Biological Chemistry, 2008 · PubMed
Research applications
NAD+ served as a substrate in the cited Sir2 and PARP enzyme studies.
Imai et al., Nature, 2000 · PubMed · Smith et al., PNAS, 2001 · PubMed · Kleine et al., Journal of Biological Chemistry, 2008 · PubMed
