Evidence profile
GHK-Cu
GHK-Cu study rows link each listed finding to its source, model or population, and endpoint.
Cited headline finding
The rat study reported collagen and glycosaminoglycan increases across the tested conditions. ↗
Mechanism scope
How cited research characterizes GHK-Cu
The cited GHK-Cu studies report collagen and glycosaminoglycan measurements in rat wound chambers and glycosaminoglycan synthesis in human fibroblast culture.
Sources: Maquart et al., Journal of Clinical Investigation 1993 ↗ · Wegrowski et al., Life Sciences 1992 ↗
Open question
What the cited GHK-Cu sources do not resolve
The cited GHK-Cu measurements are confined to their experimental models; the sources do not establish findings outside those systems.
Sources: Maquart et al., Journal of Clinical Investigation 1993 ↗ · Wegrowski et al., Life Sciences 1992 ↗
| Finding | Year | n | Model or population | Endpoint | Source | Evidence tier |
|---|---|---|---|---|---|---|
| The rat study reported collagen and glycosaminoglycan increases across the tested conditions. | 1993 | Not stated | Rat wound chambers | Collagen and glycosaminoglycan accumulation | Maquart et al., Journal of Clinical Investigation 1993 ↗ | Animal |
| The cell-culture study reported glycosaminoglycan synthesis across the tested conditions. | 1992 | Not stated | Normal human fibroblast culture | Glycosaminoglycan synthesis | Wegrowski et al., Life Sciences 1992 ↗ | In vitro |
Regulatory status
GHK-Cu appears in Health Canada's peptide-drug advisory. ↗
Reviewer: Ember Peptides source-verification editorial review · Review date: 2026-09-13