Single compoundIpamorelinSelective GHS-R1a agonist — GH release · PreclinicalCA$55.00& upEvidence tierAnimalRaun et al., European Journal of Endocrinology 19981 studyThe pharmacology study characterized ipamorelin as a selective growth-hormone secretagogue. ↗Rat and swine pharmacologyRaun et al., European Journal of Endocrinology 1998AnimalVariant10 mg5 mg
Single compoundIGF-1 LR3IGF-1 analogue — reduced IGFBP affinity · In vitroCA$55.00& upEvidence tierIn vitroPrice, Experimental Lung Research 20041 studyThe cell-culture study reported proliferative stimulation in that conditioned-medium model. ↗Cultured postnatal rat lung fibroblastsPrice, Experimental Lung Research 2004In vitroVariant10 mg0.1 mg
Single compoundTesamorelinGHRH analogue — approved indication exists · Phase 3CA$170.00Evidence tierPhase 3Falutz et al., NEJM 20072 studiesThe trial reported a −15.2% CT visceral-adipose-tissue change compared with +5.0% for placebo. ↗412 HIV-positive adults with abdominal-fat accumulationFalutz et al., NEJM 2007Phase 3Variant5 mg